How to Order

Accessing Gamifant® (emapalumab-lzsg)

Gamifant is available through our specialty pharmacy or through one of our two specialty distributors.

Specialty pharmacy


Phone: 800.850.4306

Fax: 800.823.4506

If you send a fax, please follow up with a phone call to ensure processing.

Specialty distributors

McKesson Plasma
and Biologics

Phone: 877.625.2566

Fax: 888.752.7626

Email: mpborders@mckesson.com

Online: connect.mckesson.com

McKesson Specialty Health

Phone: 855.477.9800

Online: mckessonspecialtyhealth.com

Gamifant is supplied in 10 mg/2 mL and 50 mg/10 mL
single-use glass vials.

Gamifant 10mg/2mL

NDC 72171-501-01
10 mg/2 mL (5 mg/mL)
single-use vial.

Gamifant 50mg/10mL

NDC 72171-505-01
50 mg/10 mL (5 mg/mL)
single-use vial.

Your patient's insurance coverage may dictate how Gamifant should be ordered. Contact Gamifant Patient Support Services for reimbursement support and to better understand your patient's health insurance benefits.

Gamifant Patient Support Services

Call 833.597.6530

Our support services can help guide your patients and their caregivers along the treatment journey. This program features 24/7 access to helpful tools and information.

We can help you and your patients or their caregivers navigate:

Additional resources

Get guides and tools to help you access and learn more about Gamifant.


Indication and Usage

Gamifant® (emapalumab-lzsg) is an interferon gamma (IFNγ)–blocking antibody indicated for the treatment of adult and pediatric (newborn and older) patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent, or progressive disease or intolerance with conventional HLH therapy.

Important Safety Information

Before initiating Gamifant, patients should be evaluated for infection, including latent tuberculosis (TB). Prophylaxis for TB should be administered to patients who are at risk for TB or known to have a positive purified protein derivative (PPD) test result or positive IFNγ release assay.

During Gamifant treatment, patients should be monitored for TB, adenovirus, Epstein-Barr virus (EBV), and cytomegalovirus (CMV) every 2 weeks and as clinically indicated.

Patients should be administered prophylaxis for herpes zoster, Pneumocystis jirovecii, and fungal infections prior to Gamifant administration.

Do not administer live or live attenuated vaccines to patients receiving Gamifant and for at least 4 weeks after the last dose of Gamifant. The safety of immunization with live vaccines during or following Gamifant therapy has not been studied.

Infusion-Related Reactions

Infusion-related reactions, including drug eruption, pyrexia, rash, erythema, and hyperhidrosis, were reported with Gamifant treatment in 27% of patients. In one-third of these patients, the infusion-related reaction occurred during the first infusion.

Adverse Reactions

In the pivotal trial, the most commonly reported adverse reactions (≥10%) for Gamifant included infection (56%), hypertension (41%), infusion-related reactions (27%), pyrexia (24%), hypokalemia (15%), constipation (15%), rash (12%), abdominal pain (12%), CMV infection (12%), diarrhea (12%), lymphocytosis (12%), cough (12%), irritability (12%), tachycardia (12%), and tachypnea (12%).

Additional selected adverse reactions (all grades) that were reported in less than 10% of patients treated with Gamifant included vomiting, acute kidney injury, asthenia, bradycardia, dyspnea, gastrointestinal hemorrhage, epistaxis, and peripheral edema.

Please see full Prescribing Information for Gamifant.

You may also contact Sobi at medinfo.us@sobi.com or 866-773-5274.